This is not a horror movie.
That's right, this isn't a horror movie. Oh sure, there is horror in it, but the body-melting of the Tenafly Viper drink is just the macguffin. Apart from introducing it early on in the movie it doesn't play that much of a part until near the end.
What this really is is a movie about society's invisibles, the street people on the fringes that we pretend we don't see -the winos, the derelicts, the brain-damaged, the lost, all struggling to survive one day at a time. Without the horror element I doubt if this film could have been made. And if it hadn't been made as a black comedy (often more often black than comic) it would have been completely unbearable.
Technically, it's more than accomplished. The camera-work is fluid, the image is crisp, the editing sharp, and the ensemble acting is mostly of a high standard. You are in the hands of people who know exactly what they are doing which is to create a genuinely enjoyable and original film. At least for those who can take the brutality and squalor along with the humour and the gore.
I think it's an amazing piece of work that should be far better known than it is. In its own ugly way, this is Art.